Drug Discovery and Development, Volume 2.pdf

Drug Discovery and Development, Volume 2 PDF

From first principles to real-world applications-here is thefirst comprehensive guide to drug discovery and development

Modern drug discovery and development require the collaborativeefforts of specialists in a broadarray of scientific, technical,and business disciplines-from biochemistry to molecular biology,organic chemistry to medicinal chemistry, pharmacology tomarketing. Yet surprisingly, until now, there were no authoritativereferences offering a complete, fully integrated picture of theprocess.

The only comprehensive guide of its kind, this groundbreakingtwo-volume resource provides an overview of the entire sequence ofoperations involved in drug discovery and develop-?ment-frominitial conceptualization to commercialization to clinicians andmedical practitioners.

Volume 1: Drug Discovery describes all the steps in thediscovery process, including conceptualizing a drug, creating alibrary of candidates for testing, screening candidates for invitro and in vivo activity, conducting and analyzing the results ofclinical trials, and modifying a drug as necessary.

Volume 2: Drug Development delves into the nitty-grittydetails of optimizing the synthetic route, drug manufacturing,outsourcing, and marketing-including drug coloring and deliverymethods.

Featuring contributions from a world-class team of experts,Drug Discovery and Development:
* Features fascinating case studies, including the discovery anddevelopment of erythromycin analogs, Tagamet, and Ultiva(remifentanil)
* Discusses the discovery of medications for bacterialinfections, Parkinsons disease, psoriasis, peptic ulcers, atopicdermatitis, asthma, and cancer
* Includes chapters on combinatorial chemistry, molecularbiology-based drug discovery, genomics, and chemogenomics

Drug Discovery and Development is an indispensableworking resource for industrial chemists, biologists, biochemists,and executives who work in the pharmaceutical industry.

Volume 2: Discovering Lead Molecules. Virtual screening. Utility and applications of in vitro ADMET profiling in lead discovery. Retrometabolism-Based Drug ... The drug discovery process. Progress in Drug Research, Vol. 62. (Markus Rudin, Ed.) ... ery process. 2. The drug discovery (and development) phases: overview.

3.99 MB DATEIGRÖSSE
9780470085219 ISBN
Englisch SPRACHE
Drug Discovery and Development, Volume 2.pdf

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Drug Discovery Today is a review journal, published as monthly 12 double issues. ... Dr Mark Ashton is Executive Vice President, Business Development of Evotec ... In addition, in most cases infusion parameters (infusion rate, volume, duration ... Part 2: How has HR-MS technology fundamentally changed the way we study ... Volume 2 Research and Development (W.H. Moos). ... This book reviews the important technologies used in each step of the drug discovery process; target ...

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This two-volume set provides a full account of the entire sequence of drug development, from conceptualizing the drug, creating a library of candidates, and conducting clinical trials, to optimizing the synthetic route, marketing the drug, and developing delivery methods.

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Browse the list of issues and latest articles from Drug Development and Industrial Pharmacy. List of issues Latest articles Volume 46 2020 Volume 45 2019 Volume 44 2018 Volume 43 2017 Volume 42 2016 Volume 41 2015 Volume 40 2014 Volume 39 2013 Volume 38 2012 Volume 37 2011 Volume 36 2010 Volume 35 2009 Volume 34 2008 Volume 33 2007 Volume 32 2006 Volume 31 2005 Volume 30 2004 Volume …